Institutes, Centers and Core Facilities

Thriving research centers and institutes at the University of Delaware reflect the diversity and rigor of UD’s research interests and activity as well as our commitment to improving the quality of life in Delaware and beyond. Our academic landscape is shaped by these partnerships and plays a strategic role in bringing scholars and scientists together at UD.

UNIVERSITY-WIDE RESEARCH INSTITUTES (7)
Data Science Institute
Research Institute

Data Science Institute

ADDRESS: University of Delaware Tower at STAR, Suite 614, 100 Discovery Blvd, Newark, DE 19713

DESCRIPTION:

As the vast resource of new and diverse datasets are rapidly becoming available in nearly every aspect of life, data science has the potential to advance human understanding in all branches of science and humanities, and, address grand challenges facing society. The Institute plans to combine disparate, dynamic, and distributed datasets and enable everything from predicting the future behavior of complex systems to precise medical treatments, smart energy usage, and focused educational curricula. The mission of the Data Science Institute is to accelerate research in data science, serving as a nucleating effort to catalyze interdisciplinary research collaborations across fields impacting our society.

Delaware Biotechnology Institute
Research Institute

Delaware Biotechnology Institute

ADDRESS: 15 Innovation Way, Newark, DE 19711

DESCRIPTION:

The Delaware Biotechnology Institute is a magnet for life science research and development. We support multidisciplinary, collaborative academic research at all of Delaware’s research organizations including the University of Delaware, Delaware State University, Christiana Care Health System, Nemours / AI DuPont Hospital for Children, Wesley College, and Delaware Technical and Community College. We foster academic-industrial research partnerships and work to support the local bioscience industry (from start-ups to multinationals) in partnership with the Delaware Bioscience Association. We are also committed to inspiring the next generation scientist and the professional development of their teachers through our Science for All Delawareans outreach programs.

Our Institute is the physical home to a number of research laboratories with scientists, students, and faculty working on problems related to agriculture, human health, and energy and the environment. Our Institute is also home to a number of high end instrumentation facilities that are accessible for use by the entire life science community in Delaware and our infrastructure, mission, and staff allow us to support life scientists (academic, not for profit, and industrial) from around the region. Our research has been recognized internationally and our Science Changes the World.

EQUIPMENT:

These resources are available to anyone doing research in DBI as well as to members of the academic life science community in Delaware. In some cases, specialized training and safety training is required prior to use of the equipment. For access to these resources, e-mail Robert Pekala or call (302) 831-3439.

  • Autoclaves for microbial and cell culture studies.
  • Biological Safety Hoods for mammalian, viral, plants and other specialized work.
  • Cold Rooms
  • Centrifuges (a range of rotors are available)
    • Analytical Ultra Centrifuge Beckman Coulter – Proteome Lab XL-1
    • Centrifuge – Eppendorf 5415 D (2x)
    • Ultracentrifuge – Beckman Coulter Optima LE-80K
    • Ultracentrifuge – Beckman Coulter Optima L-90K
    • Ultracentrifuge – Beckman Coulter Optima XL-100K
    • Tabletop Ultracentrifuge – Beckman Coulter Optima Max
    • Superspeed Centrifuge – Beckman Coulter Avanti J-25
    • Superspeed Centrifuge – Beckman Coulter Avanti J-20
    • Tabletop Centrifuge, refrigerated – Eppendorf 5810 R (2x)
    • Tabletop Centrifuge, non-refrigerated – Eppendorf 5810
  • Diode Array Spectrophotometer – Beckman Coulter DU 7400
  • Glassware Washers (2x)
  • Gel Documentation Station – BioRad Gel Doc XR+ (2x)
  • Incubators
    • Bacterial Incubators – Yamamoto IC 600 (2x)
    • Incubator – VWR Scientific 1525
    • Incubator – VWR Scientific 550D
    • Fisher Scientific 650D (2x)
  • Liquid Chromatography – Äkta Explorer 100
  • Liquid Scintillation Counter – Beckman Coulter LS 6500
  • Typhoon FLA 9500
  • UV/VIS Spectrophotometer – Beckman Coulter DU 640
  • UV Transilluminators (2x)
  • Shakers
    • Benchtop Platform Shaker – New Brunswick C-24
    • Floor Platform Shaker – New Brunswick C-25 (2x)
  • Water Purification Units available in each laboratory.

SERVICES:

Meeting Rooms

The Delaware Biotechnology Institute has a large meeting room on the first floor. The room can hold approximately 130 people with a seating capacity of 90. The room is equipped with audio/visual equipment and wireless internet. Also available is a formal meeting room which can comfortably hold 12 people and a video conferencing room with an informal meeting space for 6-10 people.

Reserving Space

For more information and pricing or to reserve conference rooms, please send an e-mail to events@dbi.udel.edu.

Delaware Energy Institute
Research Institute

Delaware Energy Institute

ADDRESS: University of Delaware, Newark, DE 19716

DESCRIPTION:

Energy is the driving force of our everyday life and will likely represent the currency of the future. Thus it is not surprising that the issues associated with its supply and utilization have become a dominant focus of modern society. It is now more imperative than ever to consider energy in a comprehensive and holistic manner in order to meet the needs of humanity while minimizing the costs and environmental impacts associated with energy production and consumption.

Our vision is to serve as a leadership resource with regional, national and international impact, creating and integrating new solutions to challenges in energy sufficiency and sustainability.

Delaware Environmental Institute
Research Institute

Delaware Environmental Institute

ADDRESS: 221 Academy St., 250 ISE Lab, Newark, DE 19711

DESCRIPTION:

The mission of DENIN is to conduct research and coordinate partnerships that integrate environmental science, engineering and policy in order to provide solutions and strategies that address environmental challenges.

The institute fosters a culture of scholarship that leverages the combined talents of our affiliates and fellows and adds value to environmental research, education and outreach efforts through collaborative working groups, joint proposal development and project resource coordination.

The institute’s goals are to:

  • Initiate interdisciplinary research projects
  • Support interdisciplinary academic programs
  • Forge partnerships among government agencies, nonprofits, industry, policymakers and the public
  • Coordinate and sponsor signature events and programs that provide opportunities for interdisciplinary interaction

VISION/MISSION:

Our vision is to develop an internationally recognized community of faculty, staff and students in environmental science, engineering, social science and policy, supported by state-of-the-art facilities and an effective management process, who can compete successfully for interdisciplinary grants, provide research-based educational opportunities, promote economic development and contribute to the environmental health of the state, the region and the world.

Delaware Rehabilitation Institute
Research Institute

Delaware Rehabilitation Institute

ADDRESS: Health Sciences Complex, 540 S. College Ave., Newark, DE 19713

DESCRIPTION:

The Delaware Rehabilitation Institute (DRI) provides an atmosphere where interdisciplinary research merges with education and practice to advance science. DRI is the leading national center for physical rehabilitation research. Located on UD’s Science, Technology and Advanced Research (STAR) Campus, DRI promotes high-quality interdisciplinary research within a scholarly environment that enjoins learning, discovery and community in rehabilitation practices.

SERVICES:

  • Top-ranked doctoral program in physical therapy
  • Founding partner in the Delaware Health Sciences Alliance, a collaborative partnership to advance biomedical research in Delaware
  • National Institutes of Health recognized
  • Center of Biomedical Research Excellence
  • Internationally recognized interdisciplinary Biomechanics and Movement Science (BIOMS) graduate program
  • Laboratories for research in:
    • Cytomechanics
    • Motor control
    • Rehabilitation robotics
    • Motion and gait analysis
    • Structural biology
    • Bioimaging
    • Biomechanics
    • Infant motor behavior
    • Musculoskeletal
    • Physiology
    • Athletic training
    • Motor behavior
    • Human muscle performance
    • Tissue engineering
    • Electromyography
Institute of Energy Conversion
Research Institute

Institute of Energy Conversion

ADDRESS: 451 Wyoming Road, Newark, DE 19716

DESCRIPTION:

Established at the University of Delaware in 1972, the Institute of Energy Conversion (IEC) is devoted to the research and development of thin-film photovoltaic solar cells and other photonic devices. The IEC is a totally integrated laboratory, focused on fundamental materials and device research carried out in parallel with process engineering studies and analysis of film deposition and processing. This enables the correlation of the properties of completed devices with their fabrication, all in the same lab. Close collaboration between IEC staff and industrial partners ensures that the research is relevant and includes state-of-the-art process development.

EQUIPMENT:

The IEC laboratories have a vast array of equipment – often custom- designed and built – to further our studies fulfill requests on behalf of our partners. Below is a list of current equipment being used in the IEC labs. Our equipment list changes constantly, and new pieces are added depending on project requirements.

 

Thin Film Deposition
  • Roll-to-Roll inline deposition system with four elemental effusion sources and in-situ flux control for depositing Cu(InGa)Se2 thin films onto a 15 cm wide moving web.
  • Four-source elemental evaporator for depositing Cu(InGa)Se2 onto an array of nine 2.5×2.5 cm substrates.
  • Four-source elemental evaporator for depositing Cu(InAl)Se2 onto an array of nine 2.5×2.5 cm substrates.
  • Five-source elemental evaporator for depositing Cu(InGa)(Se,S)2 onto an array of nine 2.5×2.5 cm substrates.
  • Vacuum evaporator configured for reacting Cu/In/Ga or other layers using Se and/or S evaporation sources.
  • CVD reactor for reacting Cu/In/Ga or other layers with H2Se and/or H2S gas.
  • Vapor transport deposition system for depositing II-VI compounds onto moving 10×10 cm substrates in inert or reactive ambient over wide range of pressure and temperature.
  • Three-source evaporator for depositing II-VI compounds and alloys.
    Hot wire chemical vapor deposition for depositing a-Si:H and polycrystalline Si thin films and devices.
  • Plasma enhanced chemical vapor deposition for depositing a-Si:H and
    a-SiGe:H films and devices.
  • Six-chamber, in-line, plasma enhanced chemical vapor deposition for depositing a-Si:H and a-SiGe:H films and devices.
  • Reactor for RTP treatment of films and wafers.
  • Reactor for treating films in halide vapors.
  • Chemical bath (CBD) and chemical surface (CSD) deposition of uniform CdS, ZnS and Cd1-xZnxS alloy films from 10 to 100nm thick.
  • Electron beam evaporator with three independently controlled sources for simultaneous or single element deposition of metals.
  • Electron beam evaporator with rotatable 4-source turret for depositing most metals and anti-reflection coatings.
  • Electron beam evaporator with rotatable 4-source turret and two sputtering sources.
  • Three target RF/DC sputtering system for deposition of Mo, ZnO, and ITO.
  • Four target DC magnetron sputtering system for deposition of Cu, In, Ga, Mo, and other metals.
  • Kurt Lesker six target RF/DC sputtering system with load lock chamber.
    Small sputter coater for deposition of ultra-thin metal layers.
  • Crest Ultrasonic substrate cleaning and drying facility.
  • Assorted tube furnaces and drying ovens for heat treatment and reaction in air, argon, nitrogen, hydrogen, oxygen, and hydrogen-argon.
  • Full positive photolithography capability including spin coater, Suss Mask Aligner, and well established etching procedures.
  • Circulating de-ionized water facility with 11 stations and one Barnstead NanoPure water station.
Material Characterization
  • Amray 1810T Digital Scanning Electron Microscope (15X to 100,000X) with Energy Dispersive Spectroscopy (EDS) and Electron Back-Scatter Imaging capabilities.
  • Perkin-Elmer Lambda-750 UV-visible-IR Spectrophotometer fitted with integrating sphere.
  • Philips/Norelco Scanning Wide Angle X-ray Diffractometer with diffracted beam monochromation (CuKa) and digital control/acquisition.
  • Philips Scanning Wide Angle X-ray Diffractometer with diffracted beam monochromation (CuKa, CrKa, CoKa), variable slits and digital control/acquisition.
  • Rigaku D/Max Scanning X-ray Diffractometer with symmetric theta-2 theta and asymmetric glancing incidence geometries, variable slits, hot stage (to 450°C), and computer control/acquisition.
  • Physical Electronics XPS system with load-lock sample preparation chamber and differentially pumped Ar ion gun for depth profiling.
    Digital Instruments Dimension 3100 Scanning Probe Microscope with capabilities including tunneling, electrostatic force, and magnetic force microscopy.
  • PAR computer controlled Potentiostat-Galvanostat.
  • Olympus Optical Microscope with reflected, transmitted, and polarized illumination. Accessories include Nomarski optics and dual axis stage with verniers.
  • Woollam Variable Angle Spectroscopic Ellipsometer.
  • Dektak surface profilometer.
  • ThermoScientific DXR Raman microscope.
  • ThermoScientific Nicolet 6700 FTIR.
  • Light and dark conductivity as a function of illumination intensity and temperature.
  • Hall effect measurement system.
  • Sinton lifetime testing facility.
Device Analysis
  • Current-voltage testing as a function of illumination intensity, spectral content, and temperature.
  • Two Oriel Xenon solar simulators (AM1.5 global spectra).
  • Spectral response with light and voltage bias capabilities.
  • HP4274 LCR meter for capacitance measurements as a function of illumination intensity and temperature.
  • Laser scanning facility-optical beam induced current.
  • Four-pod accelerated stress exposure facility, allowing up to 16 samples to be independently monitored and maintained under different states of controlled atmosphere, illumination, electrical bias and temperature.
  • Two-chamber accelerated stress exposure facility for up to 2ft x 2ft illuminated area in controlled temperature and humidity ambient. Other
    US Laser two-wavelength (1064nm, 532nm) laser scriber.
  • Asymtek Mechanical scriber and High resolution ink jet printer.
  • Sheet glass cutting facility.
  • Metallurgical polishing facility.
NIIMBL
Research Institute

NIIMBL

ADDRESS: 15 Innovation Way, Newark, DE 19716

DESCRIPTION:

The NIIMBL mission is to accelerate biopharmaceutical manufacturing innovation, support the development of standards that enable more efficient and rapid manufacturing capabilities and educate and train a world-leading biopharmaceutical manufacturing workforce, fundamentally advancing U.S. competitiveness in this industry.

COLLEGE-BASED CENTERS & INSTITUTES (75)
ADVANCE Institute
Research Center

ADVANCE Institute

ADDRESS: 101 Academy St., Newark, DE 19716

UD ADVANCE is meant to implement large-scale comprehensive change that will increase the representation and advancement of women faculty in academic science, technology, engineering and mathematics (STEM) careers, thereby contributing to the development of a more diverse science and engineering workforce. Explore these pages to learn more about the program’s mission, people and history as well as how you can get involved.

Agricultural Experiment Station
Research Center

Agricultural Experiment Station

The U.S. Department of Agriculture established agricultural experiment stations in connection with state land-grant universities to provide farmers with practical, science-based information.
The need for a southern Delaware location to assist in carry­ing out research projects was realized in the establishment of an Agricultural Experiment Substation near Georgetown, Sussex County, in southern Delaware, an extension of the UD experimental farm in Newark. Today, research includes vegetable crop research, specifically on lima beans and watermelon; weed management studies; agronomic crop trials for soybeans, corn and sorghum; and nutrient management studies.

Applied Science and Engineering Laboratories
Art Conservation Laboratories at Winterthur
Research Center

Art Conservation Laboratories at Winterthur

ADDRESS: 5105 Kennett Pike, Winterthur, DE 19735

The Winterthur/University of Delaware Program in Art Conservation began in 1974. It was established as a joint program following the precedent set by the Winterthur Program in Early American Culture that began in 1952, with a master’s degree awarded by the University of Delaware. Henry Francis du Pont, founder of the Museum, understood the need for conservation; he had invited Harold Plenderleith of the Rome Center to visit the Museum to advise on environmental control and fire prevention in the late 1950s. Mr. du Pont envisioned a master’s program in art conservation when a new Research Building was opened in 1969. After his death, a committee composed of University and Museum representatives continued an investigation into the establishment of a graduate program in conservation. Visits were made to existing programs at the Conservation Center of the Institute of Fine Arts of New York University and to the Cooperstown Graduate Program (now located at Buffalo State College).

Avian Biosciences Center
Research Center

Avian Biosciences Center

Meeting the growing, worldwide demand for safe and affordable poultry products produced in an environmentally sound manner will require a holistic approach that links research, management and education. The Center is established to be a center of excellence for research, education and outreach programs that will provide solutions to contemporary problems in the avian biosciences.

Bartol Research Institute
Research Institute

Bartol Research Institute

ADDRESS: 104 The Green, Newark, Delaware

The Bartol Research Institute is a Center within the Department of Physics and Astronomy whose mission is to foster excellence in research in physics and astronomy at the University of Delaware.

Biden Institute
Research Institute

Biden Institute

ADDRESS: 44 Kent Way, Newark, DE 19716

The Biden Institute, established at the University of Delaware’s School of Public Policy and Administration, is a world-class intellectual center and destination for scholars, activists, policymakers, and national leaders.

The Biden Institute’s Mission is to influence, shape, and work to solve the most pressing domestic policy problems facing America. We are a research and policy center working to bring together the sharpest minds and the most powerful voices to address our nation’s toughest problems.

The Institute is focused on the issues that have animated Vice President Biden’s public career. It is rooted in two guiding principles he has long embraced: Economic opportunity and social justice. The Institute will explore, among others, such issues as: economic opportunity for the middle class, income inequality, violence against women, civil rights and LGBT rights, civil liberties and criminal justice reform, health care reform, environmental sustainability, the state of our democracy and politics and political reform. Our approach will be dynamic – striving always to shape the conversation and serve as a leading voice in most consequential policy debates on issues facing American communities.

Core Facilities

To an extent matched by few peer institutions, the University of Delaware fulfills the Kellogg Commission’s model of an “engaged university” — an institution that makes a comprehensive and sustained contribution to the improvement of the communities it serves. UD’s research core facilities are increasingly becoming important state, national, and international assets.

Our faculty attract significant research sponsorship for projects and programs of student and public benefit, including support for federally funded national centers of excellence.

W.M. Keck Center for Microscopy and Microanalysis

W.M. Keck Center for Microscopy and Microanalysis: State-of-the-art equipment available for research and education.

Advanced Materials Characterization Lab

Advanced Materials Characterization Lab: Providing for the exchange of novel ideas and science for the next generation.

Mass Spectrometry Core Facility

Mass Spectrometry Core Facility: Offering a variety of instruments using EI, CI, FD, ESI, APCI and LIFDI for analyses in GC-MS, LC-MS, MS-MS.

UD Nanofabrication Facility

UD Nanofabrication Facility: The UDNF is part of the research wing of the 194,000-square-foot Patrick T. Harker Interdisciplinary Science and Engineering Laboratory.

Center for Biomedical and Brain Imaging

Center for Biomedical and Brain Imaging: The first research fMRI scanner in the state of Delaware.

Comparative Pathology Laboratory

Comparative Pathology Laboratory: Brightfield and fluoresence-based whole slide scanning.

DPA Material Characterization Lab

DPA Material Characterization Lab: Home to several metrology and microscopy resources.

DBI BioImaging Center

DBI BioImaging Center: A multi-user microscopy facility with state-of-the-art electron, confocal and light microscopes.

DRI Clinical Research Core

DRI Clinical Research Core: Advancing the science of rehabilitation, including osteoarthritis, stroke and pediatric mobility.

Protein Production

Protein Production: Supports the production of proteins in quantities suitable for structural studies and functional studies.

UD RESEARCH CORE FACILITIES(18)
Advanced Materials Characterization Lab
UD Research Core Facility

Advanced Materials Characterization Lab

ADDRESS: 221 Academy St, Newark, DE 19716

SERVICES:

Provide short courses on all instrumentation on a regular basis.

EQUIPMENT:

  • Phillips Xpert Powder X-ray Diffractometer
  • Rigaku Miniflex Powder X-ray Diffractometer
  • Rigaku Ultima 4 Multipurpose X-ray Diffractometer
  • Bruker D8 Multipurpose X-ray Diffractometer
  • Phillip SAXS small angle Diffractometer
  • T/A Instruments DSC,DTA,TGA,DMA,DTC
  • Metrohm IC Pro Chromatograph
  • Agilent HPLC 1260 /MS 6120
  • Agilent Cary UV Vis Spectrometer
  • Kaiser 785nm Raman Spectrometer
  • Wyatt Dynamic Light Scattering
  • Beckman Coulter LS13 320 Particle Analyzer
  • Analsys NanoIR2
  • Micromeritics Porosity Analyzer
  • Agilent ICP/MS 7500
  • Agilent AES 4100 Mass Spec.
Center for Bioinformatics & Computational Biology
UD Research Core Facility

Center for Bioinformatics & Computational Biology

ADDRESS: Delaware Biotechnology Institute, 15 Innovation Way, Suite 205, Newark, DE 19711

SERVICES:

EQUIPMENT:

  • High-Performance Compute Cluster
  • Database Server Cluster
  • 3-D Visualization Studio

Providing scientific expertise and core infrastructure support in Bioinformatics and Computational Biology for the Delaware research and education community. Available resources include bioinformatics services, consulting, training and access to computational infrastructure and software.

 

Center for Biomedical and Brain Imaging
UD Research Core Facility

Center for Biomedical and Brain Imaging

DIRECTOR: Keith Schneider
ADDRESS: 77 E. Delaware Ave., Newark, DE 19716

Sq. ft.: ~ 11,600

SERVICES:

  • Diffusion Spectrum Imaging, TimTX TrueShape and syngo ZOOMit, excellent flow sensitivity and time-resolved angiography with XR 80/200, syngo DTI with up to 256 directions, cardiac flow imaging
  • High-resolution joint imaging with excellent FatSat
  • Zoomed high-resolution imaging of the pelvis
  • High-resolution with isotropic 3D imaging
  • Up to 2x more SNR in diffusion studies
  • Advanced flow evaluation
  • Advanced multi-nuclear spectroscopy

EQUIPMENT:

Siemens 3T Magnetom Prisma scanner

Serving researchers campus-wide, statewide and throughout the region, the CBBI will advance research on psychopathology, cancer, stroke, cerebral palsy, osteoporosis and other diseases and disorders.

Center for Translational Cancer Research
UD Research Core Facility

Center for Translational Cancer Research

ADDRESS: Wolf Hall (Room 007) at the University of Delaware and the Helen F. Graham Cancer Center, Newark, DE 19713

SERVICES:

Training for researchers and PI’s for all equipment and software.

EQUIPMENT:

Flow cytometry, IVIS imaging, sample analysis, microtomy, sample preparation, image analysis

The Center for Translational Cancer Research is a multi-user facility, located in Wolf Hall on the main campus of the University of Delaware, which provides access to services including microCT, 3D computer reconstruction and flow cytometry (including cell cycle/apoptosis analysis) to university researchers and collaborators on a fee-for-service basis. Researchers using the facilities can be trained by our staff in equipment usage as well as software. Outside industrial users are accommodated when scheduling permits. Appointments can be scheduled to use the facility’s equipment by registering via the CTCR website.

Comparative Pathology Laboratory
UD Research Core Facility

Comparative Pathology Laboratory

ADDRESS: 529 S. College Ave., Newark, DE 19716

SERVICES:

Histology Services: Tissue preparation including trimming, processing, paraffin embedding and microtomy, automated H&E staining, manual special staining upon request (i.e. Gram, Masson’s trichrome, etc.)

Consultation and equipment training upon request:

Pathology Services: Microscopic analysis of tissues for diagnostic cases and research studies, consultation on experimental design, necropsy, and specimen collection and preparation, digital photography of gross or histologic specimens.

EQUIPMENT:

Leica Processor, Embedding Station, Microtome, Sakura Autostainer, Sakura Autostainer

The Comparative Pathology Laboratory provides histology and pathology support for animal diagnostic laboratories of Delaware and Maryland, researchers at the University of Delaware and its affiliates (DBI, etc.), industry and government partners of the university, and external researchers. We specialize in animal tissues and studies related to animal disease or animal models of human disease. However, we also routinely accept plant specimens for tissue processing. We strive to provide clients with customized high quality specimen preparations and thorough pathology reports to meet their individual diagnostic and research needs.

DBI BioImaging Center
UD Research Core Facility

DBI BioImaging Center

DIRECTOR: Jeffrey L. Caplan
ADDRESS: Delaware Biotechnology Institute, 15 Innovation Way, Suite 117, Newark, DE 19711

SERVICES:

We provide full-service sample preparation, data acquisition and image processing for all imaging technologies upon request.

EQUIPMENT:

Microscopes:

  • Zeiss LIBRA 120 transmission electron microscope (TEM)
  • Hitachi S4700 field emission scanning electron microscope (FE-SEM)
  • Zeiss LSM780 spectral and high sensitivity confocal microscope
  • Zeiss LSM510 NLO multi-photon confocal microscope
  • Zeiss LSM510 DUO spectral and high-speed confocal microscope
  • PECON live cell incubator for the inverted confocal microscopes
  • INSTEC thermoelectric heating and cooling for confocal microscopes
  • Zeiss ELRYA PS1 super resolution microscope
  • Custom-built total internal reflection fluorescence microscope (TIRFM)
  • TIRFM for single molecule experiments
  • Zeiss M2BIO stereo dissecting light microscope
  • Zeiss Axioplan2 upright light microscope
  • Zeiss PALM COMBI laser capture microdissection microcope (LCM)
  • Veeco Nanoscope IIIA atomic force microscope (AFM)
  • Bruker Bioscope Catalyst AFM with integrated light microscopy

Sample Preparation equipment:

  • Leica EM AFS automated freeze substitution system
  • Leica EM PACT high-pressure freezing system
  • Leica EM CPC plunge freezer
  • Leica EM IGL automated immunogold labeler
  • Reichert-Jung Ultracut E microtome for ultrathin sectioning (two)
  • PELCO Biowave 34700 microwave tissue processor
  • PELCO easiGlow Glow Discharge system
  • Leica EM KMR2 glass knife maker
  • EMCorp Microcut 1200 Vibratome
  • Denton Bench Top Turbo III for carbon or gold/palladium coating
  • Autosamdri-815B critical point dryer

Analysis tools:

  • Dell T7500 Workstation for super resolution analysis
  • Dell T5500 Workstation for visualization software
  • VSG AMIRA 5.4 analysis and visualization software
  • Perkin Elmer Volocity 6.2 analysis and visualization software
  • SVI Huygens Pro deconvolution software

The BioImaging Center is a multi-user microscopy facility containing state-of-the-art electron, confocal and light microscopes. The center is open to all academic researchers on a fee-for-service basis. Outside industrial users are accommodated when scheduling permits.

DPA Material Characterization Lab
UD Research Core Facility

DPA Material Characterization Lab

ADDRESS: 217 Sharp Lab, Newark, DE 19716

Sq. ft.: ~ 70,000

SERVICES:

Our facility is home to several metrology and microscopy resources available for use by the UD research community. Support, operation and training are provided for users to ensure quality data and timely turnaround times at reasonable rates. For all inquiries regarding daily operations, instrumentation and usage please contact, Robert Schmidt. 

Machine Shop

EQUIPMENT:

Electron Microscopy: JEOL JSM 6330F field emission scanning electron microscope

This is a ultra-high vacuum scanning electron microscope with cold field emission electron source enabling high resolution imaging. Fitted with IXRF Systems secondary electron detector and solid state backscattered detector for elemental analysis and mapping. Images stored digitally. User training is available for this microscope or samples can be submitted to a dedicated technician for imaging and data collection.

Atomic Force Microscopy: NT-MDT Ntegra Prima scanning probe microscope

This SPM device is capable of performing several measurement modes for analyzing physical properties of surfaces with high precision and resolution. The microscope is ideal for investigating small samples and has a scanning range up to 100x100x10 µm, in air only.
Available modes: Contact and Intermittent topography, magnetic force microscopy, electrostatic force microscopy, scanning capacitance microscopy, Kelvin probe microscopy, spreading resistance imaging, lithography. No user training is provided at this time, but samples can be submitted to a dedicated technician for imaging and data collection.

X-Ray Diffraction: The Rigaku IV X-ray diffractometer

A high-precision powder X-ray diffractometer with horizontal sample mount. Users can use the system as a dedicated focusing-beam system for general powder and bulk samples or switch between the Crossbeam optics for multi-layer film parallel beam, small angle scattering, micro-focus, thin film high resolution and in-plane X-ray optics. The tool uses a stepping motor with minimum step angles of 1/10000 degrees control. User training is available for this instrument, but X-Ray safety training is required before users are allowed to operate.

Physical Property Measurement System

Quantum Design’s physical property measurement system (PPMS) can perform magnetic and electro-transport measurements in sample environments having 9T fields and temperatures ranging from 2 to 340K. This PPMS is configured with the following measurements options: DC extraction magnetization, AC susceptibility, torque magnetometry, and DC/AC resistivity. A horizontal rotator is also available to perform angular studies of a sample’s magnetoresistance. A variety of platforms are available for mounting samples. Additional information and specifications can be found on the vendor’s webpage. Limited user training is available for this instrument, a dedicated operator is assigned to handle hardware set-up, sample loading/unloading and measurements.

VersaLab: Vibrating Sample Magnetometer

The Quantum Design VersaLab is a cryogen-free, cryocooler-based material characterization platform. It executes DC magnetization measurements with a temperature range of 50–400K, and 3 tesla field strength. User training is available for this instrument.

The research of our award-winning faculty covers the whole breadth of the field and extends into neighboring disciplines. The Sharp Lab offers more than 70,000 square feet of research space equipped with state-of-the-art facilities and research instrumentation. With annual research expenditures of $7.3 million, chances are we are working on something of interest to you.

DRI Clinical Research Core
UD Research Core Facility

DRI Clinical Research Core

ADDRESS: 540 South College Ave., Newark, DE 19713

SERVICES:

  • Assistance with research subject recruitment
  • Coordination of research test sessions
  • Training and intervention sessions
  • Coordinating clinical trials
  • Generate data for progress reports

EQUIPMENT:

Cytomechanics Laboratory
Carl Zeiss LSM 510 inverted confocal microscope, equipped with dry, water immersion and dipping objectives and a lens inverter; Boss LM test bench system for controlled loading of biological tissues; Instron Micro Tester 5848.

Motion Analysis Laboratory
The Department of Physical Therapy houses a 2,354-square-foot laboratory for research in motor control, biomechanics and the Running Injury Clinic. Equipment includes a VICON motion system, Bertec force platforms, Motion Lab EMG systems and an AMTI instrumented treadmill.

Neuromuscular Biomechanics Laboratory
Shared equipment within the Center for Biomedical Research includes an instrumented split-belt treadmill (Bertec), six-camera motion capture system (Motion Analysis) and 16-channel EMG system (Noraxon).

Posture and Movement Biomechanics Laboratory
Other labs within the Center for Biomedical Research maintain a seven-camera motion capture system (Qualisys), floor-mounted force plate (AMTI), tethered and telemetered EMG systems (Motion Labs), Biodex dynamometer and Asumi 5000 ultrasound unit.

Tissue Engineering Laboratory
Equipped with an Instron Microtester with a range of load cells, LVDT’s, extensometers, specimen grips and computer-based test control and data collection; a compound microscope equipped with BioQuant Imaging system for high-resolution visualization of displacement-force testing of biomaterials and biological tissues. Custom testing devices for animal loading and tissue testing; stereomicroscopes.

DRI’s state-of-the-art facility in the Health Sciences Complex at the 272-acre UD Science, Technology & Advanced Research (STAR) Campus in Newark, Delaware, will further promote collaboration among academic disciplines devoted to advancing the science of rehabilitation, including areas such as osteoarthritis, stroke, pediatric mobility and the rehabilitation of wounded warriors.

DRI Cytomechanics Core
UD Research Core Facility

DRI Cytomechanics Core

ADDRESS: 540 South College Ave., Newark, DE 19713

SERVICES:

Confocal imaging, bioimaging, live-cell imaging, mechanical loading, mechanical testing, bone and cartilage processing and histology.

EQUIPMENT:

Epifluorescence Microscopes: Upright Zeiss w/ Color Axio CamMRc5 camera; Inverted Zeiss w/ Monochrome AxioCamNRc camera and motorized stage; Upright Zeiss Image A2 w/ Color Axio CamMRc5 camera.

Confocal Microscope: Zeiss LSM510 Inverted Observe.Z1 with optional lens inverter, environmental chamber and heated stage.

Fluorescent Microscope and Calcium Imaging: Leica DMI6000B Inverted with high-speed EMCCD camera, motorized stage and environmental chamber.

>Stereomicroscope: Olympus SZx7.

Live imaging Apparatus: Isofluorane anesthesia machine; environmental chamber; incubation system (PECON System 2000).

Mechanical Testing Devices: Instron 5848 MicroTester; TA Instruments dynamic mechanical analyzer; Bose ElectroForce TestBench; custom Piezo-positioning/loading system; custom cantilever loading device; custom microindenter.

Physiological Manipulation Devices: Syringe pump (Harvard Apparatus PhD Ultra); multichannel dispenser (ISMATE IPC High Precision); catheter blood pressure measuring system (Millar); manipulators (Narishig).

Sample Prep and Histology: Diamond saws (Buehler Isomet 1000 and Isomet low speed precision); 3D table-top milling machine (Roland).

Researchers at the Delaware Rehabilitation Institute pursue a multidisciplinary, collaborative approach to address the cellular level of osteoarthritis (OA) along with prevention and treatment. The continuation of this pursuit is afforded by COBRE funding through the National Institutes of Health.

Fischer Greenhouse and the Growth Chamber Facility
UD Research Core Facility

Fischer Greenhouse and the Growth Chamber Facility

ADDRESS: 531 South College Ave., Newark, DE 19716

Sq. ft.: ~ 25,000

SERVICES:

  • Cold Storage for Plant Germplasm

EQUIPMENT:

The 13,800 ft2 Fischer Greenhouse Complex and the Growth Chamber Facilities offers:

  • Glass houses (17,000 ft2) with headhouse (5,000 ft2)
  • Growth chambers (2,300 ft2 ) and growth room (500 ft2)
  • Commercial Seed Dryer and Seed Storage Unit

A state-of-the-art plant growth facility at the University of Delaware’s College of Agriculture and Natural Resources, the Fischer Greenhouse Complex is a professionally managed suite of growth chambers and glass house facilities serving the research and education community.

Mass Spectrometry Core Facility
UD Research Core Facility

Mass Spectrometry Core Facility

DIRECTOR: Papa Nii Asare-Okai
ADDRESS: 110 Lammot duPont Laboratory, Newark, DE 19716

SERVICES:

High-resolution accurate mass measurement (HRMS) of organic and organometallic compounds using Waters GCT Premier equipped with Electron Impact (EI), Chemical Ionization (CI), Desorption Chemical Ionization (DCI), Field Ionization (FI), Field Desorption (FD) and Liquid Injection Field Desorption Ionization (LIFDI).

LC/MS and LC/MS/MS using Shimadzu LCMS 2020, Waters Q-TOF and Thermo Q-Exactive Orbitrap with Electrospray Ionization (ESI) and Atmospheric Pressure Chemical Ionization (APCI).

GC-MS (low-resolution EI only) using the Agilent 5973 system.

MALDI analysis of proteins, oligonucleotides, nanoparticles, synthetic polymers and macromolecules.

Mass directed prep purification is also available.

EQUIPMENT:

High-Performance Instrumentation Lab (Room 122, Lammot duPont Lab), Protein Sequencing, Micromass model Ultima Q Tof (Quadrupole-Time of Flight tandem mass spectrometer): This is an LC-MS-MS instrument primarily used to identify proteins by sequencing the products of a digested protein. Product molecular ions and subsequent collisional activation to generate fragments are automatic. Software generated or de novo peptide sequencing can be compared to protein databases for identification.

Protein Digester- Bruker Daltonics model Proteineer DP: This automated digest and prep station performs protein digests. Digest products can be automatically spotted to a MALDI sample plate or captured in MTP format for LC-MSMS analyses.

Open Access Instrumentation Lab (Room 108, Lammot duPont Lab)

GC-MS (Gas Chromatography-Mass Spectrometry): Agilent models 6850 GC and 5973 MS with autosampler. Used primarily for separation of small organic mixtures, incorporates a NIST library to aid identification.

LC-MS (Liquid Chromatography-Mass Spectrometry): Thermo-Finnigan model LCQ using Electrospray Ionisation (ESI) with an integrated autosampler. Used for biological samples and polar organics. The instrument can be switched between column mode for mixture separations and loop injections for quick analyses of purer samples.

MALDI (Matrix Assisted Laser Desorption Ionisation) Bruker Daltonics model Omniflex: Used primarily for biological samples to determine molecular weight and purity.

Murray V. Johnston Lab (Room 125, Lammot duPont Lab)
MALDI- Bruker Daltonics model Biflex MALDI mass spectrometer: Used for high-resolution and accurate mass measurements; automated protein identification via peptide mass maps.

The core facility is grouped into three areas; the first laboratory houses the high performance instruments for more detailed and precise analyses, a second lab houses three open-access, user-friendly instruments that are available for researchers to use 24/7, and finally, a high-performance MALDI instrument is located in Murray V. Johnston’s Lab.

NMR Laboratory
UD Research Core Facility

NMR Laboratory

DIRECTOR: Steve Bai
ADDRESS: 015 Brown Laboratory, Newark, DE 19716

Sq. ft.: ~ 4650

SERVICES:

Traditionally, the institutional support made a primary contribution to the operational budget of NMR laboratory. A user-fee structure has been established to offset the increasing expenses of maintaining the expanded NMR laboratory in terms of the number of instruments and users. The COBRE III has been providing significant contribution to the NMR laboratory operational budget. To all federally funded investigators: please acknowledge the NIH support of this COBRE-sponsored core in all your publications where you utilized the NMR core. The language for the acknowledgment can be found in a COBRE citation webpage.

EQUIPMENT:

Two solution 400 MHz NMR spectrometers, one with an auto-sampler and a cryogenic QNP probe and another with multinuclear capabilities, are available for routine proton and multinuclear NMR analysis of organic and inorganic materials. Also: two solution 600 MHz spectrometers, one with a triple-resonance cryogenic probe for biomolecular samples and another with an auto-sampler and enhanced 19F capabilities for expanded NMR applications such as high-resolution magic angle spinning (HRMAS) for semi-solid materials.

The 500 MHz solid-state NMR spectrometer is currently equipped with a 3.2 mm triple-resonance (1H, 13C and 15N) probe for biosolids and other organic solid material. The 850 MHz spectrometer is hybridized for both solution and solid-state NMR measurements. With the ultra-high magnetic field and a large collection of solution and solid-state NMR probes, the 850 MHz NMR spectrometer covers a broad range of applications from inorganic material, synthetic organic polymeric materials to structure and dynamic studies in structural biology.

In addition to the departmental NMR instrument, four NMR spectrometers with frequencies ranging from 200 to 600 MHz are used and maintained by the following research groups: Polenova, Dybowski and Rozovsky. Most of these spectrometers are dedicated solid-state NMR instruments.

  • Liquid-state NMR spectroscopy
  • Bruker AM-250 spectrometer (Tecmag Upgrade) (011 BRL) 5mm, Dual probe for 1H and 13C measurements
  • Bruker AC-250 spectrometer (Tecmag Upgrade) (011 BRL), 5mm Dual probe for 1H and 13C measurements, 5mm Proton-only probe, Variable Temperature Unit available
  • Bruker AMX360 spectrometer (011A BRL; Telephone: 831-3566), 5mm QNP probe, 5mm Broad-band probe, VT capabilities
    Bruker DRX-400 spectrometer (021 BRL; Telephone: 831-3308), 5mm QNP probe, 5mm inverse BB probe, z-axis pulsed field, gradient, VT capabilities
  • Bruker AV600 spectrometer (015BRL; Telephone: 831-4534) 5mm auto tune/match inverse PTXI probe (triple-resonance; three-axis gradients), 5mm BBO probe, 5mm inverse CryoProbe
  • Solid-state NMR spectroscopy
  • Bruker MSL-300 multinuclear spectrometer (011 BRL), 4mm CP/MAS probe, 7mm CP/MAS probe, 7mm CRAPMS probe
  • Data Workstation
  • Dell Precision workstation (Linux Redhat 7.5 and Bruker xwinnmr 3.5) for off-line data processes

The Nuclear Magnetic Resonance (NMR) Facility currently has six NMR spectrometers. The NMR facilities are located in the basement floor of the North Wing of Brown Laboratories (BRL). The 600 MHz instrument is housed in 015 BRL and the remaining spectrometers are located across the hallway in three adjacent rooms (011, 011A and 021 BRL).

Protein Production
UD Research Core Facility

Protein Production

ADDRESS: 15 Innovation Way, Newark, DE 19711

SERVICES:

The Protein Production Core Facility accepts internal and external requests for services. All work requests are initiated on a first-come, first-served basis, with University of Delaware members receiving priority and all other user requests being fulfilled as soon as possible.

We are dedicated to providing assistance in the following research areas:

Large-scale protein expression
We can perform large-scale (10-20L) protein expression in bacterial or yeast systems with our BioFlo 4500 fermentor. Please Abraham Lenhoff for further information.

Protein purification
We will purify the protein of interest from natural or recombinant sources. Our facility has two AKTA systems with the capability to purify proteins under room temperature or cold conditions. Please contact Abraham Lenhoff for further information.

Macromolecule characterization
Our facility has Proteome XL-I analytical ultracentrifuge for characterization of macromolecule interactions. Please Abraham Lenhoff for further information.

In addition, we provide consultation on experimental design and protocol development for unsupervised users (who can operate the equipment and execute experiments by themselves).

EQUIPMENT:

  • New Brunswick BioFlo 4500 fermentor (20L capacity for bacterial and yeast cell growth)
  • Avestin EmulsiFlex C5 high pressure homogenizer
  • GE Life Sciences AKTA Explorer100 and Purifier10 high-performance liquid chromatography systems
  • Beckman Coulter Proteome XL-I analytical ultracentrifuge
  • Beckman Coulter JLA 8.1000 centrifuge rotor
  • Thermo Savant SPD2010 Speedvac system

The Protein Production Core (PPC) Facility is one of the shared core facilities supported by the Center of Biomedical Research Excellence (COBRE) in Membrane Protein Production and Characterization. The PPC has modern instrumentation for large-scale expression, purification and characterization of prokaryotic and eukaryotic proteins for investigators and researchers. The core supports the production of proteins in quantities suitable for structural studies (X-ray and NMR) and functional studies (biological or catalytic). The PPC also has state-of-the-art analytical ultracentrifuge equipment for studying macromolecule interactions.

Proteomics and Mass Spectrometry Core Facility
UD Research Core Facility

Proteomics and Mass Spectrometry Core Facility

ADDRESS: Delaware Biotechnology Institute, 15 Innovation Way, Newark, DE 19711

SERVICES:

  • Protein identification
  • Shotgun proteomics
  • 2DE analysis
  • MALDI MS
  • Electrospray MS
  • Post-translational modification
  • Multiplex immunoassays

EQUIPMENT:

  • Intavis DigestPro – robotic protein digestion platform
  • AB Sciex 4800 – MALDI TOF/TOF
  • AB Sciex 5800 – MALDI TOF/TOF
  • AB Sciex QTrap Pro – ESI MS
  • AB Sciex 4000 QTrap – nanoLC/MS
  • Luminex LX200 – bead-based immunoassays

The Proteomics and Mass Spectrometry Core Facility provides services and analyses primarily based on protein/peptide separation and identification. The facility runs two MALDI TOFTOF mass spectrometers and two electrospray mass spectrometers. Sample preparation is aided by two robotic platforms that perform in-gel and in-solution enzymatic protein digestions. We offer standard workflows for protein identification and shotgun proteomics, as well as custom workflows for a range of analytical goals such as 2D gel electrophoresis and software-based image analysis, multiplex protein quantitation (isobaric label-based and selected reaction monitoring), post-translational modification analysis and multiplex bead-based immunoassays.

UD Nanofabrication Facility
UD Research Core Facility

UD Nanofabrication Facility

ADDRESS: 221 Academy St., Newark, DE 19716

Sq. ft.: ~ 8,500

The UD Nanofabrication Facility (UDNF) will enable researchers in academia, industry and government to create devices smaller than a human hair, supporting scientific advances in fields ranging from medical diagnostics to environmental sensing to solar energy harvesting. Explore our website to learn about our facility and all that we offer.

UD Sequencing & Genotyping Center
UD Research Core Facility

UD Sequencing & Genotyping Center

DIRECTOR: Kelvin Lee
ADDRESS: Delaware Biotechnology Institute, Room 246, 15 Innovation Way, Newark, DE 19711

SERVICES:

  • DNA sequencing (ABI BigDye Sanger sequencing and Illumina SBS next-generation sequencing)
  • Genotyping (fragment analysis microsatellite analysis, STR analysis)
  • PCR, qPCR, DNA preparation and analysis services (including extraction, purification, quantitation and quality scoring, fragmentation, amplification, plasmid construction and preparation).
  • Access to pyrosequencing and microarray instrumentation

EQUIPMENT:

  • llumina HiSeq 2500
  • Pacific Biosciences RSII Single-Molecule Sequence
  • ABI Prism 3130XL Genetic Analyzer
  • ABI 7500 Fast Real-Time PCR System
  • Pippin Blue DNA Size Selection System
  • Covaris S2 Adaptive Focused Acoustic Disruptor with CryoPrep
  • Agilent 2100 Bioanalyzer
  • Qubit Fluorometer
  • NanoDrop Technologies ND-1000 UV-Vis Spectrophotometer
  • MJ Research Tetrad Thermocycler
  • ABI Veriti and GeneAmp PCR System 9700 Thermocycler
  • Eppendorf Centrifuge 5804R

The DNA Sequencing & Genotyping Center provides state-of-the-art genomics and molecular biology services for University of Delaware research groups and outside users on a fee-for-service basis. R97

W.M. Keck Center for Microscopy and Microanalysis
UD Research Core Facility

W.M. Keck Center for Microscopy and Microanalysis

DIRECTOR: Chaoying Ni
ADDRESS: 250V Harker Interdisciplinary Science and Engineering Laboratory, Newark, DE 19716

SERVICES:

The laboratory staff and associated faculty members are knowledgeable in SEM, TEM and SPM and are experts in advanced microscopy of a wide range of materials. We work with users on campus and other organizations in many areas including research, research training, and consultation.

EQUIPMENT:

TEM

  • Equipment 1 Talos F200C (200kV FE-TEM)
  • Equipment 2 JEM-2010F (200kV FE-TEM)
  • Equipment 3 JEM-3010 (300kV TEM)
  • Equipment 4 Tecnai G2 12 (120kV TEM)

SEM

  • Equipment 5 Auriga 60 CrossBeam (FIB/FE-SEM)
  • Equipment 6 JSM-7400F (FE-SEM)

AFM

  • Equipment 7 Dimension-3100 V SPM
  • Equipment 8 MultiMode NanoScope V SPM

The W.M. Keck Center for Advanced Microscopy and Microanalysis (Keck CAMM) has been established since 2001 through generous grants from the W. M. Keck Foundation, the National Science Foundation and funds from the University of Delaware. This facility contributes to scientific capabilities by enabling students, faculty and other researchers in the University and from regional institutions and facilities to use state-of-the-art equipment for research and education.

It houses two 200 kV field emission transmission electron microscopes, Talos F200C and JEM-2010F, a LaB6 300kV TEM JEM-3010, an FEI 120kV Tecnai G2 12 Twin transmission electron microscope, two scanning electron microscopes (JSM-7400F and AURIGATM 60 CrossBeamTM with the AURIGATM 60 being a FIB-SEM dual beam instrument), and two scanning probe microscopes (Multimode NanoScope V and Dimension 3100 V).

X-Ray Crystallography Laboratory
UD Research Core Facility

X-Ray Crystallography Laboratory

DIRECTOR: Glenn P. A. Yap
ADDRESS: 236 Brown Laboratory, Newark, DE 19716

SERVICES:

Typical turnaround times under average conditions, from start of data-collection to completely refined structure, range from a few hours to a day.

EQUIPMENT:

Dual wavelength APEX II Duo (Mo & Cu) Bruker-AXS CCD X-ray diffractometer. Data are collected typically at 200K. Structures are solved with SHELXTL software.

The X-ray Crystallography Laboratory conducts characterizations by X-ray diffraction of small-molecule organic or inorganic single crystals. As an extension service, the facility also accepts sample submissions from other departments of the University and from local, national and international collaborators of academe and industry. The facility also serves as an ancillary graduate research laboratory for selected graduate students pursuing studies in inorganic chemistry leading to a doctorate degree.

ASSISTANCE

Compliance Hotline
Phone: (302) 831-2792

UD Research Office
Phone: (302) 831-2136
Fax: (302) 831-2828

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